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Ubiquitination : Ubiquitin conjugating enzyme E2
S. cerevisiae S. pombe Human Other species Substrate Description
Ubc1       denatured protein homologous to Ubc4 and Ubc5
Ubc2/Rad6 UbcP2     p27Kip1 complex with Rad18 (DNA repair), complex with Ubr1(N-ter rule)
Ubc3/Cdc34       p27Kip1, G1 cyclin, wee1 essential, involved in DNA replication
Ubc4 UbcP1 UBCH5/E2-F1   p53, IkB, c-Fos homologous to Ubc1 and Ubc5.
Ubc5         homologous to Ubc1 and Ubc4
Ubc6/Doa2          
Ubc7 UbcP3        
Ubc8          
Ubc9   hUBC9     essential for progression of G2/M, interacts with Rad51Hs, SUMO-1
Ubc10          
Ubc11          
Ubc12          
Ubc13          
  UbcP4 UBCH10 E2-C, UBCx   involved in degradation of M cyclin
    UBCH5A/Ubc4     UBCH5 family
    UBCH5B     UBCH5 family
    UBCH5C     UBCH5 family
    UbcH7      
    AtUBC8     UBCH5 family
    HIP-2/E2-25K   HD? huntingtin-interacting protein-2, interacts with Nedd-4