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DNA Replication : DNA polymerase
S. cerevisiae Mw (kDa)   S. pombe Human Mw (kDa) Chromosome Description
POL1/CDC17 180 essential   DNA pol alpha catalytic subunit 185   DNA replication, lagging strand
POL12 86 essential   accessory protein 68    
PRI2 58 essential   accessory protein 54 6p11.1-12  
PRI1 48 essential   DNA primase 46 12q13.3 DNA primase
POL2 256 essential   DNA pol epsilon catalytic subunit 225 12q24.3 DNA replication, leading strand, DNA repair, 3'-5' exonuclease
DPB2 80 essential   accessory protein   14q21-22  
DPB3 34 non-essential   accessory protein      
DPB3 31 non-essential   accessory protein      
DPB4 29 ?   .      
POL3/CDC2 125 essential   DNA pol delta catalytic subunit 125 19q13.3-13.4 DNA replication, leading strand, DNA repair, 3'-5' exonuclease
HYS2 56 ?   accessory protein   7  
POL4 68 essential   DNA pol beta 39 8p11-12 DNA repair, recombination
MIP1 144     DNA pol gamma     mitochondrial DNA replication, 3'-5' exonuclease
REV3 173     DNA pol zeta/Rev3-Rev7Hs   6q22 UV-damaged DNA repair
REV7 29     . 39   DNA repair, recombination
POL5 116     DNA pol eta/hRad30A     XPV responsible gene
        DNA pol theta   3q13.31 similar to Drosophila mus308 and C. elegance mus1
        DNA pol iota/hRad30B   18q21.1 similar to pol eta (hRad30A)
        DNA pol kappa      
        DNA pol lambda/DNA pol beta-N     involed in meiosis
        DNA pol mu/TdT-N   7p13 similar to TdT, act as DNA mutator.
        human DINB1   5q13 UmuC/DinB(DNA pol IV) superfamily
        human Rev1   2q11.1-11.2 template dependent deoxycytidyl transferase
        AF044578   4p16.3 family A polymerase
-       TdT     involved in TCR gene re-arrangement